Molecular Diagnostics

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Transplantation & Dermatological Panel

DiAGSure HLA B27 Detection Kit

Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammatory bowel disease, and reactive arthritis. Symptoms of ankylosing spondylitis include lower back pain and stiffness after inactivity. The disorder can be totally asymptomatic or severe and crippling. Endogenous IC ensures sample quality along with process control. Each reaction is of 25 uL volume which requires a whole blood DNA input of 10 uL per reaction. Positive controls (PC) have been so provided to run a PC per 10 samples. On the contrary, a customer can half-dilute the PC to run a single PC per 5 samples.
  • Specimen type: Whole blood
  • Strain Coverage: Detects all subtypes (1-59) of HLA B27
  • Technology: 2-plex TaqMan PCR (one for target, other for internal control)
  • Turn-around-time: 1 hr
  • Sensitivity: The sensitivity of the kit is less than 3 copies of HLA B27 cloned plasmid construct
  • Specificity: >=99%
 

HSV (Herpes Simplex Virus) Detection Test

The herpes simplex virus, also known as HSV, is an infection that causes herpes. Herpes can appear in various parts of the body, most commonly on the genitals or mouth. There are two types of the herpes simplex virus: HSV-1: primarily causes oral herpes, and is generally responsible for cold sores and fever blisters around the mouth and on the face. HSV-2: primarily causes genital herpes, and is generally responsible for genital herpes outbreaks. The herpes simplex virus is a contagious virus that can be transmitted from person to person through direct contact. Children will often contract HSV-1 from early contact with an adult who has an infection. They then carry the virus with them for the rest of their lives. Some of the symptoms associated with this virus include: blistering sores (in the mouth or on the genitals), pain during urination (genital herpes), itching, fever, swollen lymph nodes, headaches, tiredness, lack of appetite. HSV can also spread to the eyes, causing a condition called herpes keratitis. This can cause symptoms such as eye pain, discharge, and a gritty feeling in the eye.
  • Minimum sample volume: 1 mL
  • Specimen type: Whole blood, Tear, urine, genital swabs
  • Specificity: 99%
  • Technology: 2-plex TaqMan PCR (one for target, other for internal control)
  • Analytical Time: 90 min
  • Turn-around-time: 48 hrs
  • Sensitivity: 100 copies per reaction
Sample Description
Sample Description